Soluble ST2 and Cardiovascular Outcome

  • STATUS
    Recruiting
  • participants needed
    500
  • sponsor
    Nanjing Medical University
Updated on 19 February 2024
cardiovascular morbidity
heart disease
heart surgery
coronary disease

Summary

Cardiac surgery induces hemodynamic stress on the myocardium, and this process can be associated with significant cardiovascular morbidity and mortality. Soluble suppression of tumorigenicity 2 (sST2) is biomarker of myocardial remodeling and fibrosis; however, little is known regarding their potential association with cardiovascular events. This study aimed to investigate the release of sST2 and its association with cardiovascular events undergoing cardiac surgery.

Details
Condition Cardiovascular Disease
Age 18years - 90years
Treatment soluble ST2
Clinical Study IdentifierNCT04460131
SponsorNanjing Medical University
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

age 18 years
Congenital heart disease requiring surgery
Valvular heart disease requiring surgery
Arrhythmia requiring surgery
Aortic dissection requiring surgery
Coronary heart disease requiring surgery

Exclusion Criteria

age <18 years
pregnancy
severe renal dysfunction (creatinine >200mol/L)
not capable of understanding or signing informed consent
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