Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma

STATUS

Recruiting
participants needed

36
sponsor

Hospital de Infecciosas Francisco Javier Muniz

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Updated on 19 February 2024

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critical illness

shock

organ failure

mechanical ventilation

respiratory distress

acute respiratory distress syndrome

covid-19

critically ill

acute respiratory distress

Summary

This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.

Description

This study aims to use convalescent plasma as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit. Donors must have anti-SARS CoV2 antibodies. Recipients must be critically ill Covid-19 patients on mechanical ventilation.

Details

Condition	SARS coronavirus, Severe Acute Respiratory Syndrome, COVID19
Age	18years - 100years
Treatment	Convalescent plasma
Clinical Study Identifier	NCT04468009
Sponsor	Hospital de Infecciosas Francisco Javier Muniz
Last Modified on	19 February 2024

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Eligibility		Yes	No	Not Sure
Inclusion Criteria
	Age: 18 years or more
	Patient with Covid-19 confirmed with nuclear acid testing
	Critically ill patients with Covid-19 on mechanical ventilation. Potencially critically ill patients (with acute respiratory distress syndrome, septic shock and/or multiple organ failure) with Covid-19
	Diagnosed with acute respiratory distress syndrome
	Informed consent
Exclusion Criteria
	No consent
	Symptoms for a period longer than 20 days
	Not detectable by acid nuclear testing within 48 hours prior to elegibility
	Descompensated congestive heart failure, in which receiving 500ml of intrasvascular volume signifies a life risk
	History of severe adverse events or anaphylaxis to plasma components

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Step 3 Enroll in the clinical study

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Step 4 Get your study results

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma