COVID-19 and Cancer Patients

  • STATUS
    Recruiting
  • participants needed
    1000
  • sponsor
    Imperial College London
Updated on 19 February 2024
cancer
covid-19
SARS
acute respiratory syndrome (sars)

Summary

Routinely collected data will be used to assess the morbidity and mortality of cancer patients following a positive COVID-19 infection.

Description

The SARS-CoV-2, (COVID-19) virus of the coronavirus family is believed to have bene transmitted from animal to human. On 12th March 2020, the World Health Organisation (WHO) declared this particular coronavirus outbreak a pandemic.

How COVID-19 affects people is still not widely understood. Some people who have tested positive for the virus have been asymptomatic while others, who were otherwise well and healthy before infection, have died. Currently, information obtained so far suggests that most COVID-19 illness, however older people and people with severe comorbidities such as heart and lung disease and diabetes, seem to be at higher risk of developing serious COVID-19 illness.

This research is a retrospective, non-interventional study whose aim is to describe the features of COVID-19 infection specifically in cancer patients; to investigate its severity in this particular population and evaluate the long-term outcomes by means of medical charts review of consecutive patients co-diagnosed with SARS-CoV-2 infection and malignancy.

Patients will be identified from electronic medical records and entered into a pre-designed database. All information used will have been previously collected as part of routine standard of care and will involve but is not limited to: blood test results, prior and current anti-cancer therapy, medical history and most importantly clinical outcomes, such as response to any treatment provided for COVID-19 and patients' survival in relation to baseline clinic-pathologic profile. All data will be collected by each patient's team and will be anonymised and stored in a password-protected NHS computer.

Details
Condition Cancer, Sars-CoV2
Age 18-100 years
Clinical Study IdentifierNCT04393974
SponsorImperial College London
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

The investigators will evaluate and include consecutive patients observed in
the outpatients and inpatients facility of the study centre meeting all the
following CRITERIA
Be 18 years of age
Have a confirmed diagnosis of malignancy of any type
Have a confirmed diagnosis of SARS-CoV-2 infection

Exclusion Criteria

Patients will not be entered in the study database when one or more of the
following CRITERIA are present
Unconfirmed diagnosis of SARS-CoV-2 infection
Insufficient clinical/follow up data
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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