Optimizing Platelet Isolation (The Cell Study)

  • STATUS
    Recruiting
  • participants needed
    20
  • sponsor
    Arkansas Children's Hospital Research Institute
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Updated on 19 February 2024
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Summary

The research study is about blood cells (platelets) and their power houses (mitochondria). The investigators want to learn about their behavior in order to ensure that our laboratory procedures are generating optimal results.

Description

The objectives of this study are to assess platelet activation following standard laboratory procedures used in the process of measuring platelet mitochondrial function, and to determine the optimal amount of digitonin needed to permeabilize platelet cell membrane.

Details
Condition Healthy
Age 25years - 35years
Clinical Study IdentifierNCT04470505
SponsorArkansas Children's Hospital Research Institute
Last Modified on19 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Age 25-35
All races
All ethnicity
5 - 30 BMI

Exclusion Criteria

smoking
Aspirin intake
Recreational drug use
Alcohol intake more than 3 times per week
Self-reported possibility of current pregnancy
Known diagnosis of
Pre-diabetes
Diabetes
High cholesterol
High triglycerides
Hypertension
Anemia
Autism spectrum disorder
Attention deficit hyperactivity disorder (ADHD)
Attention deficit disorder (ADD)
Severe asthma
Refusal to stop taking nutritional supplements
Any other pre-existing medical condition that requires daily medication as determined by the investigators to affect outcome of interest
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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