Hypertension and Controlled Hypotension in the Elderly

  • STATUS
    Recruiting
  • participants needed
    102
  • sponsor
    Zhang Lei
Updated on 19 February 2024
cancer
anesthesia
hypertension
delirium
postoperative delirium

Summary

Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor

Description

Postoperative delirium has a higher incidence in elderly patients after general anesthesiaand It is closely related to the type of surgery, the length of surgery, and the patient's physique.Because head and neck maxillofacial radical surgery requires free flap transplantation and longer duration,and hemorrhage is more when the primary focus is removedIntraoperative blood pressure reduction is needed to reduce bleedingtherefore, hypoperfusion of craniocerebral blood flow will occur.Low cerebral perfusion is closely related to the occurrence of postoperative delirium.Patients undergoing this type of surgery have more preoperative complicationshypertension is particularly common.Therefore, this study mainly studied the correlation between the preoperative blood pressure level and the controlled hypotension level in patients with radical head and neck and maxillofacial tumors and the incidence of postoperative delirium.

Details
Condition Delirium
Age 60-100 years
Treatment hypertension
Clinical Study IdentifierNCT04433416
SponsorZhang Lei
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients who underwent radical anesthesia for oral and maxillofacial malignant tumors in our hospital
ASA grade is -
Patient is older than 60 years

Exclusion Criteria

The patient has mental and mental disorders (eg schizophrenia, Alzheimer's disease)
There was severe anemia before operation (Hb<80g/L)
Patients had cerebral vascular complications such as cerebral infarction and lacunar infarction before operation
Patients who do not cooperate with this trial
Long-term use of sedative drugs or analgesics
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