TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
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- STATUS
- Recruiting
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- participants needed
- 40
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- sponsor
- Tizona Therapeutics, Inc
Summary
This is a Phase 1, multicenter, open-label, multiple-dose, dose-escalation and dose-expansion study to evaluate the safety, tolerability, PK, and pharmacodynamics of TTX-080 monotherapy in subjects with advanced or metastatic solid tumors known to express HLA-G.
This first-in-human (FIH) study has been designed to evaluate the safety, tolerability, and preliminary antitumor activity of TTX-080 as monotherapy in adults with unresectable or metastatic solid tumors known to express HLA-G.
Details
| Condition | Solid Tumor, Adult |
|---|---|
| Age | 18-100 years |
| Treatment | TTX-080 |
| Clinical Study Identifier | NCT04485013 |
| Sponsor | Tizona Therapeutics, Inc |
| Last Modified on | 19 February 2024 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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