Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma
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- STATUS
- Recruiting
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- End date
- Jul 5, 2027
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- participants needed
- 226
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- sponsor
- Sun Yat-sen University
Summary
Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease the rate of disease progression and improve the survival outcome of patients with unresectable locally recurrent nasopharyngeal carcinoma compared with those treated with concurrent chemo-radiotherapy alone.
Description
Through multicenter, open-label, randomised clinical trials, patients with unresectable locally recurrent nasopharyngeal carcinoma are randomized into concurrent chemo-radiotherapy plus concurrent and adjuvant PD-1 treatment group and concurrent chemo-radiotherapy alone group. The efficacy and safety of patients between these two groups are compared.
Details
| Condition | Chemotherapy, Chemotherapy, Radiation Oncology, Carcinoma, vulvar dysplasia and carcinoma, drug therapy, Radiotherapy, radiotherapeutic, Nasopharyngeal Cancer, Nasopharyngeal Cancer, vulvar dysplasia and carcinoma, PD-1 Treatment |
|---|---|
| Age | 18-70 years |
| Treatment | Toripalimab plus concurrent chemo-radiotherapy, Concurrent chemo-radiotherapy |
| Clinical Study Identifier | NCT04453813 |
| Sponsor | Sun Yat-sen University |
| Last Modified on | 19 February 2024 |
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