Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19
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- STATUS
- Recruiting
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- participants needed
- 240
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- sponsor
- University of Sao Paulo
Summary
The SWITCH-COVID trial will randomize patients with COVID-19 that are currently using renin-angiotensin system inhibitors for treating hypertension to maintain the therapy during in-hospital stay or switch the therapy to other antihypertensive classes.
Description
Patients eligible for the study, after signing informed consent will be randomized 1:1 for maintenance of renin-angiotensin system inhibitors or switching the antihypertensive therapy for other classes according to a pre-specified protocol.
Patients are going to be followed during hospital stay for evaluation of clinical endpoints. Also blood and urine samples will be acquired for evaluation of renin-angiotensin system activation.
Details
| Condition | COVID19, Angiotensin II Receptor Antagonist Adverse Reaction |
|---|---|
| Age | 18-80 years |
| Treatment | Renin-angiotensin system inhibitors |
| Clinical Study Identifier | NCT04493359 |
| Sponsor | University of Sao Paulo |
| Last Modified on | 19 February 2024 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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