Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy
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- STATUS
- Recruiting
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- participants needed
- 300
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- sponsor
- Fourth Military Medical University
Summary
Our previous study (Am. J. Gastroenterol. 2017 04;112(4)) showed that water exchange (WE) colonoscopy was able to increase the detection of flat adenomas as well as overall ADR. We hypothesized that WE based whole-colon acetic acidAA staining might be useful to improve the detection of flat lesions compared with WE alone.
Description
Water exchange colonoscopy was performed as described previously (Am. J. Gastroenterol. 2017 04;112(4)). Patients were randomly allocated to WE group or WE+AA group. In WE+AA group, water containing 1% of AA was used during insertion of colonoscopy instead of water alone. A bottle of 20ml pure AA was placed abutting the water pump, which make it possible to keep patients blinded to group allocation. Endoscopist using a high-definition wide-angle Olympus or Fujinum colonoscope performed all of the colonoscopies, with a withdrawal time of at least 6 min. The observation was initially performed without the assistance of cap or the use of magnification or electronic staining (NBI, BLI, LCI or AFI et al.). Scopolamine butylbromide or glucogon was not routinely administrated.
Details
| Condition | Adenoma Colon |
|---|---|
| Age | 40-70 years |
| Treatment | acetic acid staining, Water exchange colonoscopy |
| Clinical Study Identifier | NCT04464135 |
| Sponsor | Fourth Military Medical University |
| Last Modified on | 19 February 2024 |
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