Brain Imaging in Babies Study

  • STATUS
    Recruiting
  • participants needed
    790
  • sponsor
    King's College London
Updated on 19 February 2024
x-rays
brain imaging
autism
pervasive developmental disorder
deficit
covid-19
attention deficit hyperactivity disorder
attention deficit disorder
attention deficit

Summary

The aims of the BIBS Study

The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age. Working with children from a variety of backgrounds and communities, the investigators use a combination of state-of-the-art diagnostic tools such as MRI scans alongside traditional behavioural assessments to capture the earliest information on infant brain development.

The focus of the BIBS study

MRI scanning is a safe way of producing detailed images using strong magnetic fields and radio waves. It does not use X-ray. Along with learning more about brain development in general, the investigators also try to identify features that may in future help predict whether a child will or will not develop traits of conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). Long-term, this may help target useful interventions early on, helping children who are most in need.

Since COVID-19 arrived in the United Kingdom (U.K.) in 2020, the investigators have been given ethical approval to include testing for this infection in the mothers and children participating in the study. This may provide an opportunity to better understand how mother and baby respond to infections. The investigators particularly welcome mothers who have had a positive COVID-19 test during their pregnancy to join the study.

Details
Condition Pervasive developmental disorder, Oppositional Defiant Disorder, Attention deficit hyperactivity disorder, Covid 19, Neurodevelopmental Conditions
Age 16years - 75years
Clinical Study IdentifierNCT04443179
SponsorKing's College London
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Pregnant mothers with and without confirmed COVID-19
Infants with and without an immediate family history of Autism Spectrum and neurodevelopmental conditions
Based in England, UK

Exclusion Criteria

based on further screening
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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